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Aggressive Approach in the Treatment of Acute Lead Encephalopathy with an Extraordinarily High Concentration of Lead
Arch Pediatr Adolesc Med 152:1100-1104, Gordon,R.A.,et al, 1998
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Article Abstract
In this case, aggressive gut decontamination with whole bowel irrigation and triple chelation therapy with British anti-Lewistie, EDTA, and oral succimer was well tolerated and seemed effective for rapidly deleading the child. The extent to which her lead concentration increased while being treated with oral succimer alone necessitated further chelation with EDTA. Further evaluation is necessary to determine if triple chelation therapy is an appropriate method for severe lead intoxication, and if the use of whole bowel irrigation should be considered in heavy metal intoxication.
 
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BAL
basophilic stippling of red blood cells
chelation therapy
children
EDTA(ehtylenediamine tetraacetic acid)
encephalopathy
erythrocyte
lead and the nervous system
lead poisoning
nausea and vomiting
pain,abdominal
peripheral blood smear
peripheral blood smear,abnormal
treatment of neurologic disorder
vision,failure of in childhood
visual acuity,decreased
visual loss
walking,difficulty with

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